CRENO brings AI-powered diabetic retinopathy screening to primary care — no ophthalmologist on-site, no specialist equipment, no delay. One image. A clinical-grade result in under 30 seconds.
82%
Weighted F1 Score
97%
Severe DR Recall
<30s
AI Result Time
creno.health / imaging
AI Classification
Proliferative DR
Stage 5 — Urgent
Confidence
97%
⚑ Urgent referral required
Patients
24
Screenings
118
Priority
3
Why CRENO
Early detection saves sight.
98% of severe vision loss from DR is preventable. CRENO puts clinical-grade retinal screening in the hands of any primary care doctor — no specialist required.
AI Classification
5-class DR grading in under 30 seconds with 82% weighted F1.
Live Vitals
Bluetooth sensors capture SpO₂, heart rate & temperature.
PDF Reports
Instant clinical reports and referral letters for every screening.
Appointments
Full scheduling and patient management built in.
What is CRENO
A complete diabetic retinopathy screening platform for primary care
CRENO combines AI-driven retinal image analysis, physiological monitoring, and a clinical web portal into a single integrated workflow — deployable in any primary care or community clinic across the Caribbean.
Built from the ground up for resource-limited settings, CRENO replaces the need for specialist referrals at the screening stage. Doctors capture a fundus image with a smartphone adapter, upload it in seconds, and receive an AI classification with a confidence score and clinical recommendation.
Retinal image AI classification
EfficientNetV2-S trained on 3,662 fundus images (APTOS 2019)
5-class DR severity grading
No DR · Mild · Moderate · Severe · Proliferative
Bluetooth vitals integration
SpO₂, heart rate, temperature, blood pressure via ESP32
Clinical web portal + patient app
Doctor dashboard, PDF reports, appointment management
Role-based access control
Separate portals for clinicians, patients, and admins
Why it matters
Diabetic retinopathy is the leading cause of preventable blindness worldwide
In the Caribbean, where diabetes prevalence rates are among the highest globally, the burden of DR is severe — yet access to ophthalmologists is limited, and most cases go undetected until irreversible damage has occurred.
Regular retinal screening can prevent up to 98% of severe visual loss. The challenge is doing it affordably, consistently, and at scale in primary care settings that lack specialist equipment.
537M
adults living with diabetes globally — Caribbean regions disproportionately affected
1 in 3
people with diabetes will develop diabetic retinopathy — often without symptoms
98%
of severe vision loss from DR is preventable with timely screening and treatment
<30s
is all it takes for CRENO's AI to classify a retinal image with clinical-grade accuracy
Platform Preview
A clinical platform built for speed and precision
Real-time AI results, patient records, analytics, and referrals — in a single unified interface.
97% Confidence · Proliferative DR
Real-time Vitals Connected
CRENO Clinical Portal — Dr. Harrison
Clinical
Dashboard
Patients
Retinal Imaging
Appointments
Tools
Analytics
Reports
Dashboard Overview
Total Patients
24
Screenings
118
High Priority
3
Recent Screenings
MJ
M. JohnsonSevere DR
AC
A. ClarkeNo DR
RT
R. ThomasModerate DR
Retinal Analysis
AI Result
Proliferative DR — Stage 5
97%
How it works
From clinic to AI result in under a minute
No ophthalmologist on-site required. CRENO integrates into your existing primary care workflow seamlessly.
01
Register Patient
Clinician opens the CRENO mobile app and registers the patient with basic demographic and health history.
02
Capture Fundus Image
Retinal image taken via smartphone adapter and uploaded to encrypted cloud storage over Wi-Fi or mobile data.
03
Record Vitals
Bluetooth sensor captures heart rate, SpO₂, temperature, and estimated blood pressure simultaneously.
04
AI Classification
EfficientNetV2-S model classifies the image into one of five DR severity levels in under 30 seconds.
05
Clinical Action
Doctor reviews the result on the web portal and generates a PDF report with recommendations and referral guidance.
Why CRENO
Four capabilities. One platform.
CRENO combines three complementary technologies into a single, cohesive platform — purpose-built for Caribbean primary care environments with limited infrastructure.
AI Retinal Classification
EfficientNetV2-S deep learning model trained on APTOS 2019 achieves 82% weighted F1 across five DR severity classes. Post-hoc threshold optimization improves Moderate DR recall to 79%. Test-time augmentation further boosts reliability.
Physiological Monitoring
Custom ESP32-based hardware integrates MAX30102 pulse oximetry and MLX90614 infrared temperature sensing via Bluetooth. Blood pressure is estimated from pulse wave features — providing a complete vitals snapshot at the point of screening.
Clinical Platform
React Native mobile app handles patient registration, image capture, and Bluetooth vitals collection. A web clinical portal supports doctor dashboards, patient management, screening history, analytics, appointments, and PDF report generation.
Clinical Features
Everything a modern screening workflow needs
Designed for clinicians. Built for the Caribbean. Ready for scale.
Retinal Imaging & AI
EfficientNetV2-S model provides 5-class DR severity grading with confidence scoring, test-time augmentation, and threshold-optimized recall for clinically important cases.
82% F1
Vitals Monitoring
SpO₂, heart rate, temperature and estimated blood pressure via custom Bluetooth hardware.
Patient Management
Full patient registry with demographics, screening history, and longitudinal tracking.
Appointments
Scheduling system synced to patient mobile app with reminder notifications.
Medical Reports
One-click PDF generation for referrals, clinical summaries, and patient handouts.
Population Analytics
Dashboard insights on DR prevalence, screening rates, and clinical trends by cohort.
Cloud Sync
Firebase-backed real-time sync between mobile app and web portal, with offline support.
Role-Based Access Control
Separate secure portals for clinicians, patients, and system administrators — each with purpose-built workflows and data access controls aligned to their role in the care pathway.
Who benefits
Built for clinics, doctors, and patients alike
CRENO is designed to work for every stakeholder in the primary care ecosystem — from the clinic administrator to the patient seeing their results for the first time.
Clinics & Health Facilities
No specialist equipment required
Expand service offerings without additional hires
Population-level screening analytics built in
Affordable pricing for public health clinics
Doctors & Clinicians
AI-assisted decisions with full confidence scores
Manage patient lists, screenings, and appointments
One-click PDF referral and clinical reports
Urgent cases surfaced immediately on the dashboard
Patients
Access results and history through the patient portal
Download a PDF summary of your screening record
View and manage upcoming appointments
Doctor-assigned health goals tracked over time
Impact
Numbers that demonstrate clinical readiness
Our Mission
"To make specialist-level eye disease detection accessible to every primary care clinic in the Caribbean — regardless of resources, infrastructure, or specialist availability."
Built at the University of the West Indies
Developed as a capstone research project with clinical supervision, now advancing through the FutureHEALTH Incubator programme.
Designed for Afro-Caribbean populations
Standard retinal AI tools frequently underperform on darker fundus pigmentation. CRENO's model accounts for this — where others don't.
82%
Weighted F1 Score
EfficientNetV2-S · APTOS 2019
97%
Severe DR Recall
Post-hoc threshold optimization
<30s
AI Result Time
From upload to classification
5
DR Severity Classes
No DR through Proliferative
Caribbean Context
Designed for resource-limited Caribbean healthcare
Standard ophthalmology equipment costs tens of thousands of dollars and requires specialist operators. CRENO was designed from the ground up to function on a smartphone, work in clinics with intermittent connectivity, and produce results that generalist doctors can act on immediately.
The Caribbean faces a diabetes epidemic and a specialist shortage simultaneously. CRENO was built to close that gap — starting with sight.
Smartphone-based capture
3D-printed optical adapter turns any smartphone into a fundus camera.
Remote monitoring
Physiological data and retinal history tracked over time. Deterioration flagged automatically.
Trained with attention to Afro-Caribbean retinal characteristics where standard tools underperform.
Testimonials
Trusted by clinicians and health researchers
"CRENO dramatically reduces the time between screening and clinical decision. For our rural clinics, having AI-assisted DR grading available instantly changes how we manage diabetic patients."
DR
Dr. Rachel Bowen
Family Physician, Kingston, Jamaica
"The integration of Bluetooth vitals with retinal screening in a single workflow is exactly what primary care in the Caribbean has needed. The platform is intuitive and the AI results are actionable."
SM
Dr. Samuel Mitchell
Medical Officer, Trinidad & Tobago
"From a public health perspective, CRENO represents the kind of scalable, low-cost screening solution that can meaningfully reduce preventable blindness across our region."
PA
Prof. Angela Prescott
Public Health Researcher, UWI
FAQ
Common questions about CRENO
CRENO's EfficientNetV2-S model achieves a weighted F1 score of 82% across five DR severity classes, with a 97% recall rate for Severe and Proliferative DR — the cases where timely referral is most critical. Post-hoc threshold optimization ensures Moderate DR recall reaches 79%, minimizing clinically meaningful missed diagnoses.
CRENO requires a smartphone (Android or iOS) running the CRENO mobile app, a lightweight 3D-printed optical adapter for fundus imaging, and the custom ESP32 Bluetooth vitals sensor module. No expensive ophthalmology equipment is needed. The web clinical portal works in any modern browser.
The mobile app supports offline data entry and image capture. Images are queued for upload and AI analysis when connectivity is restored. Core patient records are cached locally. The web portal requires an internet connection to access the Firebase-backed database and AI backend.
All patient data is stored in Google Firebase with role-based access controls enforced at the database rule level. Retinal images are stored in Firebase Storage with private access tokens. The AI backend is hosted on Google Cloud Platform. Data handling is aligned with HIPAA best practices and Caribbean data protection standards.
CRENO has three role types: Doctors/Clinicians who access the full clinical dashboard; Patients who can view their own results, appointments, and health goals; and System Administrators who manage doctor approvals and platform accounts. All accounts are reviewed and approved before access is granted.
Get In Touch
Request access or schedule a demonstration
Whether you represent a ministry of health, a research institution, a hospital network, or a primary care clinic — we'd like to hear from you.
Or sign in directly →
Firebase-secured data
HIPAA-aligned handling
UWI-developed technology
FutureHEALTH Incubator
Ready to Modernize Retinal Screening?
Access the CRENO clinical portal to start screening patients, reviewing AI results, and generating reports — built for primary care providers across the Caribbean.
CRENOClinical Portal
AI retinal screening for Caribbean primary care
Clinician-grade diabetic retinopathy detection in under 30 seconds — no ophthalmologist required.
EfficientNetV2-S model, 82% weighted F1 across 5 severity classes
Real-time vitals via Bluetooth — heart rate, SpO₂, temperature, blood pressure
Patient records, appointment scheduling, and PDF report generation
Firebase-backed · GCP AI backend · HIPAA-aligned data handling
82%
Weighted F1 score
97%
Severe DR recall
<30s
AI result time
5
DR severity classes
CRENO Portal
Sign in to your account
Select your role to continue
Provider Portal
CRENO
Doctor
Welcome back
Sign in to your clinical dashboard
Patient Portal
CRENO
Patient
Your health records
Sign in to view your screening results
View your retinal screening report
Download your PDF report
View upcoming appointments
For the best experience, use the CRENO mobile app on your phone.
Clinical Command Center
Good morning, Doctor
Loading…
— patients
— screenings
— urgent cases
— appointments
Total Patients
—
Under your care
Screenings
—
All time
High Priority
—
Severe / Proliferative
Appointments
—
Upcoming
Quick Actions
Common clinical workflows
Recent Screenings
Latest AI analyses
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Urgent Cases
Requires immediate review
Today's Appointments
Today
Patients
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Retinal Imaging
Upload a new image or select a previous screening
Run AI analysis
Your AI server is HTTP-only. Open this file directly (file://) or add SSL to your GCP VM for https:// hosting.
⚠ CORS error — AI server not reachable from the browser
Your Flask server needs to allow browser requests. Add this to your server file:
pip install flask-cors
# At the top of your Flask file:
from flask_cors import CORS
# Right after app = Flask(__name__):
CORS(app)
Then restart your GCP server. The mobile app works because React Native bypasses CORS — browsers enforce it. Image has been saved to Storage regardless.
Create printable screening reports for patients and referrals
Options
Report preview
Select a patient to preview the report
Appointments
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Patient Health Portal
Welcome back
Loading your health summary…
— screenings
— upcoming appointments
Screenings
—
Total
Last Result
—
—
Upcoming
—
Appointments
Latest Screening
Most recent AI analysis
Next Appointment
Upcoming schedule
My Vitals
Latest recorded
Vitals Over Time
Health trends from your screenings
Heart rate (bpm)
SpO₂ (%)
Temperature (°C)
Blood pressure (systolic)
Screening results
All retinal screenings performed by your doctor
History
Appointments
Your upcoming and past appointments
All appointments
My report
A personal summary of your latest screening
Options
This is an unofficial personal summary for your own records.
Preview
Building preview…
Patient Education
Understanding Diabetic Retinopathy
What your result means and what to do next
What is diabetic retinopathy?
Diabetic retinopathy (DR) is an eye condition caused by damage to the blood vessels in the retina due to prolonged high blood sugar. It is one of the leading causes of vision loss in working-age adults, but when caught early it is highly treatable.
Regular retinal screening is the single most effective way to detect DR before symptoms appear.
Severity levels explained
No DRNo signs detected. Continue annual screening and maintain good blood sugar control.